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These plastic-backed TLC sheets are made with a different polymeric binder system than the standard flexible-backed silica gel sheets (cat# 158017 & 159017) and will therefore exhibit different separation characteristics. To help the end user decide which plate to choose we have listed below some areas of documented use for the HRF silica plates. sennisides propranolol rhein pindolol lawsone mercury in organic compounds zinc in water organomercury compounds juglone labetalol (and others also)